Table 1. Differentially expressed miRNAs in the Mertk−/− RPE.
Table shows down-regulated (A) and up-regulated (B) miRNAs in the Mertk−/− RPE. The columns “Morning” and “Evening” represent fold changes in the Mertk−/− RPE over the WT RPE in the comparisons obtained from morning or evening groups, respectively. “-” indicates changes of <1.5-fold.
| (A) Down-regulated | ||
|---|---|---|
| miRNA | Morning | Evening |
| miR-96 | −3.5 | −2.4 |
| miR-190b | −2.3 | −2.0 |
| miR-130b | −2.3 | −2.5 |
| miR-1193 | −2.3 | −2.2 |
| mmu-let-7e | −2.0 | −2.7 |
| miR-882 | −3.3 | −1.5 |
| miR-467f | −3.3 | 2.7 |
| miR-551b | −2.9 | - |
| miR-494 | −2.6 | - |
| miR-497 | −2.1 | - |
| miR-881 | −2.0 | - |
| miR-503 | −2.0 | - |
| miR-125b-5p | −2.0 | - |
| miR-669e | - | −2.8 |
| miR-297b-3p | - | −2.7 |
| miR-466a-5p | - | −2.5 |
| miR-466c | - | −2.2 |
| miR-466b-5p | - | −2.2 |
| miR-466d-5p | - | −2.2 |
| miR-1187 | - | −2.0 |
| miR-574-5p | - | −2.0 |
| (B) Up-regulated | ||
|---|---|---|
| miRNA | Morning | Evening |
| miR-467b | 3.04 | 4.22 |
| miR-667 | 4.92 | 1.94 |
| miR-124 | 6.61 | 2.42 |
| miR-669h-3p | 2.30 | 1.59 |
| miR-615-3p | 2.34 | 1.50 |
| miR-130b | 2.44 | - |
| miR-466d-3p | 2.73 | - |
| miR-466f | 1.86 | 2.1 |
| miR-485 | 1.67 | 2.3 |
| miR-291b-5p | - | 2.0 |
| miR-325 | - | 2.0 |
| miR-714 | - | 2.1 |
| miR-138 | - | 2.1 |
| miR-706 | - | 2.2 |
| miR-133b | - | 2.2 |
| miR-199a-3p | - | 2.4 |
| miR-466l | - | 2.5 |
| miR-467f | −3.30 | 2.7 |
| miR-133a | - | 2.9 |
| miR-483 | −1.62 | 3.1 |
| miR-763 | - | 4.3 |