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. 2015 Jan 6;10(4):501–508. doi: 10.1007/s11523-014-0353-6

Table 1.

Afatinib IC50s compared to gefitinib IC50s of SCCHN cell lines

Cell line Afatinib IC50 (μM) Confidence interval Gefitinib IC50 (μM)
SCC25 0.0102 9.796e-005 to 1.062 5–10
HN5 0.06412 0.009348 to 0.4398 0.05–0.5
SCC58 0.3405 0.07144 to 1.623 >100
SQ20B 0.5176 0.08746 to 3.064 1–5
MSK921 1.174 0.6654 to 2.071 1–5
HN31 1.225 0.8320 to 1.805 1–5
SCC61 1.903 0.6092 to 5.942 5
SCC28 1.951 0.7886 to 4.827 >5
Detroit 562 2.485 0.9399 to 6.569 5–50
SCC35 8.008 5.645 to 11.36 100