Table 4.
Multivariable Analyses of Factors Associated with Referral for & Receipt of Surgical Intervention for Hepatocellular Carcinoma
| Characteristics | Referral for Surgical Intervention | Receipt of Surgical Intervention | ||
|---|---|---|---|---|
| AOR (95% CI) | P-Value* | AOR (95% CI) | P-Value* | |
| Demographic Characteristics | ||||
| Age in years | 0.98 (0.98, 0.99) | <.001 | 0.99 (0.97, 1.00) | .127 |
| Male sex | 0.75 (0.63, 0.90) | .001 | 0.73 (0.50, 1.07) | .104 |
| Race | .025 | .038 | ||
| White (Reference) | 1.00 | -- | 1.00 | -- |
| African-American | 0.89 (0.73, 1.10) | .291 | 1.02 (0.64, 1.61) | .941 |
| Hispanic | 0.72 (0.47, 1.09) | .123 | 0.64 (0.27, 1.50) | .304 |
| Asian | 1.48 (1.05, 2.11) | .027 | 2.29 (0.90, 5.79) | .081 |
| Other/Unknown | 1.44 (0.87, 2.37) | .154 | 0.41 (0.19, 0.86) | .018 |
| Insurance type | <.001 | .508 | ||
| Private (Reference) | 1.00 | -- | 1.00 | -- |
| Medicare | 0.83 (0.69, 1.00) | .053 | 1.23 (0.84, 1.80) | .295 |
| Medicaid | 0.58 (0.46, 0.75) | <.001 | 1.29 (0.67, 2.11) | .538 |
| Other | 0.62 (0.46, 0.82) | .001 | 0.81 (0.45, 1.45) | .312 |
| Income, $1000s | 1.00 (0.99, 1.01) | .125 | 1.00 (0.99, 1.01) | .708 |
| Other Characteristics | ||||
| SEER summary stage | <.001 | <.001 | ||
| Localized (Reference) | 1.00 | -- | 1.00 | -- |
| Regional | 0.32 (0.27, 0.38) | <.001 | 0.94 (0.64, 1.38) | .721 |
| Distant | 0.09 (0.06, 0.12) | <.001 | 0.27 (0.15, 0.50) | <.001 |
| Proximity to high volume surgical center (<30 minutes) | 0.79 (0.68, 0.92) | .002 | 0.83 (0.60, 1.15) | .273 |
Abbreviations: CI: confidence interval; AOR: adjusted odds ratio; SEER: National Cancer Institute Surveillance, Epidemiology and End Results program.
*
P-values were calculated using multivariable logistic regression analyses. Educational attainment and rurality were not included due to multi-collinearity.