Table 7. Crossover analysis in genotypes-menopausal status interaction study on cervical cancer.
Genotype | Menopausal status | Patients (N = 1486) n (%) | Controls (N = 1536) n (%) | OR(95%CI) a | P a |
---|---|---|---|---|---|
AA/GA | Menopause | 642(48.15) | 759(51.53) | 1 | |
AA/GA | Premenopausal | 471(34.79) | 517(35.10) | 1.80(1.42–2.29) | <0.001 |
GG | Menopause | 105(7.75) | 117(7.94) | 1.06(0.79–1.41) | 0.700 |
GG | Premenopausal | 126(9.31) | 80(5.43) | 3.18(2.24–4.52) | <0.001 |
Interaction | P b = 0.018 |
aAdjusted for age, smoking status, family history of any cancer and parity.
b P value for multiplicative interaction.