Table 3. Comparison between childhood subjects with or without optic disc morphological changes.

	ONH/PPA unchanged group	ONH/PPA change group	P Value
	(n = 40)	(n = 42)
Age at baseline, year	5.47 ± 4.08	4.84 ± 3.50	0.472*
Gender, Male:Female	18:22	19:23	0.983 †
Duration between baseline and final follow-up, years	3.47 ± 3.08	2.84 ± 1.96	0.290*
Sperical equivalent, diopter
Baseline	-1.84 ± 1.64	-2.54 ± 1.89	0.094*
Final	-2.87 ± 1.65	-4.37 ± 1.74	<0.001*
Changes	-1.02 ± 1.06	-1.85 ± 1.36	0.004*
Central corneal thickness, μm Intraocular pressure, mmHg	562.88 ± 40.84	564.60 ± 27.40	0.907*
Baseline	23.34 ± 3.24	15.73 ± 2.19	<0.001*
Mean during follow-up	16.48 ± 3.41	16.38 ± 2.79	0.884*
Horizontal disc diameter to vertical disc diameter ratio
Baseline	0.911 ± 0.104	0.891 ± 0.107	0.422*
Final	0.921 ± 0.103	0.831 ± 0.111	0.001*
Changes	0.009 ± 0.037	-0.060 ± 0.069	<0.001*
Maximum peripapillary width to vertical disc diameter ratio
Baseline	0.075 ± 0.116	0.107 ± 0.115	0.227*
Final	0.069 ± 0.096	0.212 ± 0.119	<0.001*
Changes	-0.006 ± 0.045	0.104 ± 0.057	<0.001*

Data are presented as mean ± standard deviation.

ONH = optic nerve head; PPA = peripapillary atrophy.

*Comparison among the three groups by Student’s t-test.

^†Comparison among the three groups by Chi-square test.