Table 4.
Odds ratios of genotypes and alleles in different subgroups with idiopathic scoliosis (IS).
| Subgroup | Genotype, allele | p value | OR [95% CI] |
|---|---|---|---|
| General | GG versus CC | 0.002 | 3.5 [1.54–7.98] |
| G versus C | 0.0006 | 2.02 [1.35–3.03] | |
|
| |||
| AIS (n = 61) | GG versus CC | 0.003 | 3.75 [1.52–9.27] |
| G versus C | 0.005 | 2.3 [1.28–4.16] | |
|
| |||
| Familial history of IS (n = 22) | GG versus CC | 0.007 | 10.5 [1.33–83.03] |
| G versus C | 0.002 | 3.26 [1.52–7.01] | |
|
| |||
| Cobb angle >40° (n = 62) | GG versus CC | 0.002 | 4.25 [1.63–11.05] |
| G versus C | 0.005 | 2.3 [1.28–4.16] | |
|
| |||
| Males (n = 15) | GG versus CC | 0.1 | 7.27 [0.77–68.89] |
| G versus C | 0.02 | 3.27 [1.17–9.16] | |
|
| |||
| Females (n = 65) | GG versus CC | 0.01 | 3.02 [1.24–7.39] |
| G versus C | 0.03 | 1.9 [1.06–3.38] | |
A value of p < 0.05 was considered to be statistically significant. AIS indicates adolescent idiopathic scoliosis; OR: odds ratio; CI: confidence interval.