(c) Total IPSS

	2004	2007	p value∗
MS (−)	11.15 ± 9.34	13.16 ± 9.33	0.133
MS (+)	10.39 ± 8.54	13.4 ± 8.98	0.007
p value†	0.402

^∗2004 versus 2007 IPSS in each group (paired t-test).

^†2004 versus 2007 IPSS between MS (−) and MS (+) (2-way ANOVA test).