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. 2015 Jul 7;6:107. doi: 10.3389/fendo.2015.00107

Table 1.

Inhibition of europium-labeled insulin (Eu-insulin) for binding to the IR-A.

Insulin IGF-II qIGF-I S597
IC50 (nM) 1.57 ± 0.33 15.21 ± 0.18 4.88 ± 0.8 0.75 ± 0.16
Rel. IC50 (%) 100 10.3 32.2 209

The concentration at which 50% of Eu-insulin binding was inhibited by each peptide (IC50 nM) is given. The IC50 relative to that of insulin is also shown. Values are the means ± SEM of three independent experiments.