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. 2015 Jun 29;212(7):1095–1108. doi: 10.1084/jem.20142110

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© 2015 Rahimpour et al.

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Figure 6. — Most MAIT cells are RORγt^hi and produce IL-17A. (A) MAIT cells, NKT cells (CD1d–α-GalCer tetramer⁺), and conventional TCR-β⁺ T cells were labeled with antibodies specific for RORγt and T-bet. (B) Samples from thymus, spleen, and lung were stimulated for 4 h in vitro with PMA/ionomycin, and expression of RORγt and T-bet and production of IFN-γ and IL-17A by MAIT and NKT cells were analyzed by flow cytometry. Data are representative of four experiments, with a combined total of eight mice.