Figure 2.
Schematic overview of ligand-stimulated SR signal transduction. OxLDL-stimulated activation of intracellular signaling pathways is exemplified by SR-A, SR-B2 (CD36) and SR-E1 (LOX-1). Different endocytosis pathway are denoted 1–3 (1) caveolae-mediated uptake, (2) lipid-raft dependent uptake, and (3) clathrin-independent pathway.