Figure 1.

Anatomy of the zebrafish pronephros. (A) The zebrafish pronephros develops from bilateral fields of renal progenitors (purple) that emerge from the intermediate mesoderm (IM) and are located lateral to the paraxial mesoderm (PM, red) that gives rise to the somites (denoted by their number along the embryo axis respective to each nephron segment in panel B); (B) At 24 hours post fertilization (hpf), the two nephrons have formed and consist of a series of segments that include: podocytes (P, light green) that contribute to the blood filter, neck (N, dark green), proximal convoluted tubule (PCT, orange), proximal straight tubule (PST, yellow), distal early (DE, sky blue), corpuscles of Stannius (CS, red), distal late (DL, dark blue), and pronephric duct (PD, black). The numbers indicate the position of each nephron segment with respect to the somites. [Figure adapted from [45], through terms of the Creative Commons License of the Authors].