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. 2015 Jul 7;5:11872. doi: 10.1038/srep11872

Figure 4. TSG-6 inhibits CCR2+ monocyte recruitment to CNV lesion.

Figure 4

(a) Immunohistochemical staining of the RPE-choroid-scleral flat mounts at day 3 showed a massive infiltration of CCR2+ cells in the area of CNV after injury. There was significantly less infiltration of CCR2+ cells in TSG-6-treated eyes. (b) Similarly, Iba+ cells largely infiltrated the CNV lesion, and TSG-6 treatment significantly reduced Iba+ cell infiltration. Original magnification × 200. Scale bar: 100 μm. Photographs shown are representative of two independent experiments (each with four eyes per group), and data are presented as mean + SEM. *p < 0.05.