Figure 2. The N-terminus constricts the barrel lumen of Pput2725.
(A) Views from the extracellular side showing a cartoon (top panel; colored by B-factor) and a molecular surface model (bottom panel). (B) Cut-away surface view showing the internal channel. The constriction is indicated with an arrow. (C) Surface view from the extracellular side of Pput2725 lacking the N-terminus, showing a large channel. For comparison, a rainbow surface model is shown for E. coli NanC, which is involved in the uptake of N-acetylneuraminic acid.