Table 1. Performance of 3 sole encoding schemes on different size of dataset.

Method	(+) sites	(−) sites	Ratio	Sn (%)	Sp (%)	ACC (%)	MCC
AF	112	127	0.88:1	67.20	66.13	69.51	0.403
	365	370	0.99:1	72.00	73.07	75.11	0.461
	853	937	0.91:1	68.31	69.43	72.30	0.408
	1530	1630	0.94:1	69.37	68.21	70.15	0.391
	2107	2018	1.04:1	75.33	76.86	74.94	0.477
KNN	112	127	0.88:1	57.00	52.3	58.29	0.237
	365	370	0.99:1	60.14	58.12	59.50	0.281
	853	937	0.91:1	68.22	63.10	67.20	0.306
	1530	1630	0.94:1	68.73	65.16	69.75	0.362
	2107	2018	1.04:1	75.35	71.03	72.39	0.407
CKSAAP	112	127	0.88:1	82.77	80.30	83.37	0.633
	365	370	0.99:1	82.27	80.63	82.84	0.617
	853	937	0.91:1	81.02	80.12	81.27	0.623
	1530	1630	0.94:1	77.84	79.70	80.56	0.612
	2107	2018	1.04:1	80.02	79.33	80.41	0.605