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. 2015 Jul 7;5:150. doi: 10.3389/fonc.2015.00150

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Copyright © 2015 Kraan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Top: 1-D profile along the z-axis of the measured (black) and MC simulated activity (red) induced by a 95 MeV proton beam impinging on a PMMA target during 118 s. Bottom: the same but for the 2 Gy treatment plan, delivered in 145 s. Inter-spill (left), beam-off (center), and all together (right) are displayed separately. Adapted from Ref. (116).