Table 2.
Control (C) n = 62 | Alcoholic (A) n = 37 | HIV infection (H) n = 33 | HIV + alcoholism (HA) n = 38 | P‐valuea | |
---|---|---|---|---|---|
Age | 48.33 ± 20.42 | 48.47 ± 10.61 | 50.00 ± 9.13 | 50.97 ± 6.56 | 0.7981 |
Sex (M/F) | 35/27 | 24/13 | 22/11 | 25/13 | 0.6887 |
Handedness scoreb | 24.23 ± 12.30 | 24.00 ± 13.55 | 24.06 ± 11.09 | 26.59 ± 14.23 | 0.7826 |
Body mass index | 25.54 ± 4.30 | 26.83 ± 4.43 | 25.28 ± 3.76 | 25.26 ± 4.19 | 0.3212 |
Systolic blood pressure | 124.66 ± 16.88 | 122.69 ± 15.01 | 124.55 ± 12.55 | 127.75 ± 14.98 | 0.5670 |
Diastolic blood pressure | 71.89 ± 9.05 | 73.08 ± 11.74 | 73.30 ± 9.13 | 75.75 ± 9.73 | 0.3241 |
Heart rate | 67.02 ± 10.66 | 68.86 ± 11.73 | 67.91 ± 14.78 | 68.50 ± 11.37 | 0.8851 |
Socioeconomic statusc | 26.82 ± 12.06 | 41.00 ± 12.99 | 40.21 ± 15.13 | 43.08 ± 11.45 | 0.0001: C > A = H = HA |
Education (years) | 15.87 ± 2.29 | 13.54 ± 2.33 | 13.42 ± 2.89 | 13.16 ± 2.22 | 0.0001: C > A = H = HA |
National Adult Reading Test IQ | 114.03 ± 7.83 | 106.78 ± 9.69 | 105.36 ± 9.58 | 105.87 ± 8.25 | 0.0001: C > A = H = HA |
Dementia Rating Scale | 140.19 ± 2.72 | 138.73 ± 4.35 | 136.42 ± 5.30 | 136.21 ± 4.48 | 0.0001: C = A > H = HA |
Beck Depression Inventory‐II | 2.85 ± 3.28 | 8.31 ± 5.53 | 10.67 ± 9.38 | 10.94 ± 8.42 | 0.0001: C < A = H = HA |
Global assessment of functioning | 84.45 ± 8.57 | 68.49 ± 10.69 | 76.09 ± 9.52 | 68.84 ± 8.54 | 0.0001: C > H > A = HA |
Lifetime alcohol consumption (kg) | 18.75 ± 55.53 | 1319.42 ± 1057.16 | 68.01 ± 63.40 | 828.87 ± 620.43 | 0.0001: A > HA > C = H |
Hepatitis C positive | 1 | 7 | 10 | 18 | 0.0001: C < A < H < HA |
Smoker (current or past) | 8 | 22 | 12 | 21 | 0.0001: HA = A > H = C |
CD4 cell count | — | — | 587.36 ± 276.66 | 538.45 ± 331.75 | 0.5059 |
Viral load (cml) | — | — | 9187 ± 26 103 | 7923 ± 38 264 | 0.8748 |
CNS penetration effectiveness (CPE) | — | — | 5.15 ± 3.27 | 6.58 ± 3.42 | 0.0197: HA > H |
Self‐defined ethnicity: Caucasian | 36 | 16 | 12 | 7 | N/A |
Self‐defined ethnicity: Hispanic | 1 | 3 | 6 | 8 | N/A |
Self‐defined ethnicity: African American | 13 | 17 | 15 | 22 | N/A |
Self‐defined ethnicity: other | 12 | 1 | 0 | 1 | N/A |
Analyses of variance and follow‐up t‐tests or Pearson's chi‐squared test.
RH = 14–30; LH = 50–70.
Lower score = higher status.
CNS = central nervous system; HIV = human immunodeficiency virus.