Skip to main content
. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Nanomedicine (Lond). 2015 Jun;10(11):1685–1692. doi: 10.2217/nnm.15.64

Figure 8. Mild hyperthermia of a primary tumor stimulates systemic antitumor immune response that inhibits growth of tumor rechallenge.

Figure 8

Experimental plan is the top timeline, 2° B16 refers to rechallenge to test systemic immune response. Lower left growth curve is for rechallenge on the same side as the primary tumor removed previously, lower right growth curve is for rechallenge on the contralateral side. Note that rechallenge tumors on either side are suppressed equally, demonstrating true systemic immune response.

***p < 0.001.