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. Author manuscript; available in PMC: 2015 Jul 7.
Published in final edited form as: Nature. 2004 Oct 21;431(7011):1011–1017. doi: 10.1038/nature02964

Figure 3.

Figure 3

CDK1 is needed for DSB resection. a, The 5′ to 3′ resection of DSB ends was analysed in the indicated mutants and at different points in the cell cycle by loss of the HO-cut EcoRI restriction fragment in a strain lacking HML or HMR. b, ChIP analysis of binding of RPA (left), Rad51 (centre) and Mre11 (right) to DSB ends in a donorless strain4,6, in asynchronous or G1 cells and in G2/M-arrested cells with or without Sic1 inhibition of CDK1. Where error bars are shown, results are means ± s.d. c, Lack of Rad53 phosphorylation in mre11Δ G2/M-arrested cells, compared with other conditions.