Table 2.
Association of different patient characteristics with depression (BDI) and quality of life (SF-36) scores
| BDI | Physical functioning | Physical role | Bodily pain | General health | Vitality | Social functioning | Emotional role | Mental health | |
|---|---|---|---|---|---|---|---|---|---|
| ALSFRS-R ↓ | ↑ (p < 0.001) | ↓ (p < 0.001) | 0.092 | - | 0.731 | ↓ (p < 0.01) | 0.175 | 0.774 | 0.052 |
| ALSFRS-R bulbar ↓ | 0.345 | - | - | ↑ (p < 0.01) | - | 0.116 | 0.864 | - | 0.555 |
| Disease duration | - | - | - | 0.113 | - | - | - | - | - |
| Gender | - | - | - | - | - | - | - | - | - |
| Onset | - | Sig. ↓ for spinal onset (p < 0.01) | Sig. ↓ for spinal onset (p < 0.001) | 0.743 | - | - | - | - | - |
| Age ↑ | 0.126 | 0.072 | - | - | 0.058 | - | ↓ (p < 0.05) | - | 0.292 |
| BDI ↑ | n.a. | 0.132 | ↓ (p < 0.001) | ↓ (p < 0.05) | ↓ (p < 0.001) | ↓ (p < 0.001) | ↓ (p < 0.001) | ↓ (p < 0.001) | ↓ (p < 0.001) |
-: p-value >0.2 in the simple regression, variable not included in the final multiple regression model
n.a.: not applicable
ALSFRS-R: Amyotrophic Lateral Sclerosis Functional Rating Scale – Revised
BDI: Beck Depression Inventory