Table 1.
Patient number | 27 |
| |
Age (years, range) | 30 (19-60) |
| |
Men/women | 19/8 |
| |
Total DLI number (range per patient) | 55 |
One DLI vs. >1 (patients) | 10 vs. 17 |
>1 DLI (range) | 2-5 |
| |
Donor | |
Matched related/parent | 17 (63%) |
Matched unrelated | 10 (37%) |
| |
Conditioning regimen | |
Fludarabine with melphalan or cyclophosphamide +/- ATG* | 25 |
Others | 2 |
| |
Patients who had a previous autograft | 21 (75%) |
No prior autograft | 6 (25%) |
| |
Time to progression after autograft (months, range) | 5 (1-21) |
| |
Time from disease progression after allotransplant to first DLI (months, range) | 4 (1-34) |
| |
Concomitant chemotherapy** | |
Yes | 10 (37%) |
No | 17 (63%) |
DLI: Donor leukocyte infusion. ATG: Antithymocyte globulin.
For patients receiving a matched unrelated donor transplant.
Chemotherapy administered prior to at least one of the DLIs.