Table 1. Demographics and clinical characteristics *.
Variable | Cohort, n=69 |
---|---|
Age | 57 (46-68) a |
Female (%, n/total) | 48% (33/69) |
Race (%, n/total) | |
Black/African American | 14% (10/69) |
White | 86% (59/69) |
APACHE II | 26.0 (20.2-32.0) a |
ICU admission diagnosis (%, n/total) | |
Sepsis/acute respiratory distress syndrome | 35% (24/69) |
Surgery | 29% (20/69) |
Airway protection/upper airway obstruction | 13% (9/69) |
Myocardial infarction/congestive heart failure | 9% (6/69) |
GI bleed/hemorrhagic shock | 4% (3/69) |
Other | 10% (7/69) |
Total Lorazepam (mg) | 7 [0.8-64] |
Total Fentanyl (mcg) | 5375 [1150-12350] |
Total Propofol (mg) | 0 [0-3291] |
Time in burst suppression, minutes | 6.4 (1.0-58.0) a |
Time under BIS of 40, minutes | 67 (2-827) a |
Post-coma delirium, (%, n/total) | 61% (42/69) |
Time to resolution of delirium, hours | 25 (0-71) a,b |
Median (interquartile range)
Results for the 49 patients who had resolution of delirium during the study period (n=22) or were never delirious (n=27).
Abbreviations: APACHE = Acute Physiology and Chronic Health Evaluation severity of illness score; BIS = Bispectral Index fronto-temporal EEG monitor, GI = gastrointestinal; ICU = Intensive Care Unit