Fig. 1.

Genotyping of mice and tumor burden in MDR2 mice. a) Mouse genotype was confirmed by PCR. 380 bp represented wild type MDR2 gene 180 bp product represents mutant MDR2 gene, mwm equals 100 bp standard. b) 12 mo MDR2^−/+ control mouse liver. c) 12 mo MDR2^−/− liver and d) Tumor burden in MDR2^−/− mice 12-18 mo