Table 1.
Circulating markers of inflammation in smokers with OPD-CB
| Marker | Inclusion (n=60) | Exacerbation (n=38) | P-value |
|---|---|---|---|
| MPO (µg/mL) | 27 (15–62) | 38 (16–570) | <0.01 |
| NE (µg/mL) | 44 (131–102) | 53 (23–212) | >0.05 |
| CRP (mg/L) | 2.3 (2.0–19.0) | 6.5 (0.3–300) | <0.001 |
| Leukocytes (×109/L) | 7.1 (4.5–13.5) | 8.3 (5.4–16.0) | <0.01 |
| Neutrophils (×109/L) | 4.1 (2.3–9.6) | 5.5 (3.1–13.0) | <0.01 |
Abbreviations: CRP, C-reactive protein; MPO, myeloperoxidase; NE, neutrophil elastase; OPD-CB, obstructive pulmonary disease and chronic bronchitis.