Table 2.
The relationship between miR-182 expression and clinicopathological characteristics in human HCC patients
| Variables | All patients | miR-182 expression | P value | |
|---|---|---|---|---|
| (n = 36) | lowa | higha | ||
| Age (years) | ||||
| ≤55 | 12 | 7 | 5 | 0.725 |
| >55 | 24 | 11 | 13 | |
| Gender | ||||
| Male | 28 | 13 | 15 | 0.691 |
| Female | 8 | 5 | 3 | |
| Size of tumor (cm) | ||||
| ≤5 | 16 | 12 | 4 | 0.018* |
| >5 | 20 | 6 | 14 | |
| Number of tumor | ||||
| Single | 20 | 12 | 9 | 0.5 |
| Multiple | 16 | 6 | 9 | |
| Portal vein invasion | ||||
| Negative | 25 | 16 | 9 | 0.027* |
| Positive | 11 | 2 | 9 | |
| TNM staging | ||||
| I, II | 21 | 13 | 8 | 0.176 |
| III | 15 | 5 | 10 | |
| Grade | ||||
| Well + Moderate | 27 | 15 | 12 | 0.09 |
| Poor | 9 | 3 | 6 | |
| AFP (ng/ml) | ||||
| ≤400 | 10 | 6 | 4 | 0.711 |
| >400 | 26 | 12 | 14 | |
For analysis of correlation between miR-182 expression and clinical features, fisher exact tests were used. Results were considered statistically significant at P <0 .05 *
aThe median expression level was used as the cut-off. Low expression of miR-182 in 18 patients was classified as values below the 50th percentile. High miR-182 expression in 18 patients was classified as values above the 50th percentile