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. 2015 Jul 6;210(1):935–945. doi: 10.1083/jcb.201412068

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© 2015 Lim et al.

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Figure 5. — Proposed scheme for a series of events that result from the phosphorylation or dephosphorylation of PrxI at the centrosome. Red solid arrows indicate the direction of the reactions resulting from PrxI phosphorylation, whereas the blue arrows indicate the direction of those resulting from PrxI dephosphorylation. Black arrows indicate the reactions catalyzed by the designated enzymes or induced by H₂O₂. PP_Ox denotes the oxidized forms of PP1 and PP2A, and PP_Re denotes their reduced forms. RSH, thiol-containing reductant such as glutathione or thioredoxin; CycB, cyclin B. See Discussion for details.