Table 1.

Summary of the Search for Human-Specific TF-Binding Sites

Regulatory Proteins	hESC Genome	Associated with Repeats	Percent within Repeats	Primate-Specific Sites	Human-Specific Sites	Human-Specific Sites within Repeats	Percent within Repeats	LTR/LINE Embedded	Percent within LTR/LINE
NANOG	88,351	13,200	14.9	29,130 (33%)	826 (0.9%)	824	99.8	532	64.4
CTCF	87,883	10,021	11.4	29,018 (33%)	591 (0.7%)	590	99.8	104	17.6
POU5F1	29,740	6,619	22.3	14,003 (47%)	2,386 (8%)	2,383	99.9	116	4.9
RNAPII	30,585	ND	ND	12,012 (39%)	319 (1%)	319	100.0	5	1.6

Note.—NANOG-, CTCF-, and POU5F1-binding sites were determined by the ChIP-Seq method in the H1-hESC line (Kunarso et al. 2010; hg18 database counts); RNAPII-binding sites were determined by the ChIA-PET method in the MCF7 and K562 cell lines (Li et al. 2012; hg19 database counts); ND, not determined.