Table 1.
Mouse strain | Liver | Urothelium | ||
---|---|---|---|---|
| ||||
β-Hexa | β-GCa | β-Hexa | β-GCa | |
Wild-type | 118 ± 64 | 162 ± 81 | 887 ± 368 | 267 ± 133 |
Buff | 136 ± 93 | 119 ± 9 | 1947 ± 313 | 375 ± 107 |
β-Hexosaminidase (β-Hex) and β-glucocerebrosidase (β-GC) activities are expressed as nanomoles of substrate hydrolyzed/mg protein/h at 37°C. (α = 0.05,n = 3). The two-group t-test was used to compare enzyme activities. The β-Hex activity in urothelium of Buff mice was significantly higher (p > 0.05) than that in wild-type mice, while no significant difference (p < 0.05) in the β-GC activity was observed when wild-type and Buff mice are compared. Also enzyme activities in the liver were not significantly different in wild-type and mutant mice.