Table 3.
Initial cohort: nominal associations of SNPs with relapse-free survival (RFS, p<0.05) in Cox regression models adjusted for stage.
| SNP | Alleles | Gene | HR | 95% CI | P value | Q value |
|---|---|---|---|---|---|---|
| rs4246229 | A>G | KRAS | 0.71 | 0.54 to 0.94 | 0.0168 | 0.1120 |
| rs34176876 | A>- | KRAS | 0.72 | 0.55 to 0.95 | 0.0191 | 0.1120 |
| rs1570360 | G>A | VEGFA | 1.39 | 1.03 to 1.87 | 0.0290 | 0.1428 |
| rs1951795 | C>A | HIF1A | 1.47 | 1.03 to 2.11 | 0.0341 | 0.1428 |
| rs11549465 | C>T | HIF1A | 1.62 | 1.02 to 2.57 | 0.0392 | 0.1428 |
| rs542403 | A>G | FRS2 | 0.66 | 0.44 to 0.98 | 0.0404 | 0.1428 |
| rs2076139 | C>T | MAPK11 | 0.70 | 0.49 to 0.99 | 0.0417 | 0.1428 |
SNPs are ranked by significance of SNP-RFS associations. The associations with p>0.05 are available upon request.