Figure 3.

MSCs transplantation promotes the recovery of bowel tissue injury. Bowel tissue from normal control mice showed intact intestinal crypts without inflammatory cell infiltration (A). After induction of colitis, epithelial barrier disruption, crypt and gland loss with condensed inflammatory cell infiltration were detected (B). Three days after the withdrawal of DSS, partial recovery of collapsed intestinal crypts were present (C), and the mice that were MSCs-transplanted showed a recovery in a shorter time frame compared to controls (D). Both control (E) and the transplanted mice (F) had similar profiles 7 days after the cessation of the toxin. The sections were stained with H & E. Magnification is 100 ×.