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Effect of the neutralization of endogenous interleukin-17A (IL-17A) on inflammation and fibrosis in rats with sterile pericarditis (SP). Representative histological sections stained with (A) H&E and (B) Masson’s trichrome at 4 days after surgery. Original magnification, x400. Treatment with anti-IL-17A mAb resulted in a significant decrease in the number of infiltrating inflammatory cells and fibrosis.
