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. 2015 May 8;36(1):83–92. doi: 10.3892/ijmm.2015.2204

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Copyright © 2015, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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Changes in the activity of tissue inhibitors of MMPs (TIMPs) in the atrial samples at 4 days after surgery. (A) A representative reverse gelatin zymogram is shown. Dark bands indicate undigested gelatin stained with Coomassie blue, representing the zones of gelatinase inhibition. The migration positions of TIMP-2 and glycosylated TIMP-3 are indicated. Molecular mass markers (M) are indicated. (B) Quantification of reverse gelatin zymography. The data are presented as relative densitometric units.^**P<0.01 vs. Sham; ^##P<0.01 vs. IgG2a control. Sham, sham-operated rats; SP, rats with sterile pericarditis.