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. 2015 May 26;36(1):309–315. doi: 10.3892/ijmm.2015.2223

Figure 2.

Figure 2

Effects of G581R and L450F on the steady-state inactivation kinetics of KV4.3/KChIP2-encoded K+ currents. (A) Currents showing steady-state inactivation curves recorded from KV4.3-WT, KV4.3-G581R and KV4.3-L450F with KChIP2. (B) The stimulation protocol used for steady-state inactivation. (C) Mean ± standard error (SE) normalized current amplitudes were plotted as a function of conditioning potential for the •, KV4.3-WT/KCHIP2; ■, KV4.3-G581R/KChIP2; and ▲, KV4.3F450F/KChIP2 encoded K+ currents. The solid lines represent the best (single) Boltzmann fits to the mean ± SE normalized data. G581R and L450F have no effects on the KV4.3/KChIP2-encoded channel voltage dependence of steady-state inactivation. The error bars represent standard error of the mean for ≥7 cells from each group.