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. 2015 Jul 2;9:899–911. doi: 10.2147/PPA.S83333

Table S3.

Major findings and themes presented in each of the articles included in the review

References Major findings or themes
Anandadas et al2 Most men who chose RP wanted physical removal of the cancer (60%). Approximately 27% of men who chose EBRT did so from fear of other treatment options. The main reason for choosing BT was more convenient for their lifestyle (39%).
Berry et al3 Personal perceptions of outcomes were highly influential. Longevity and bowel, bladder, and sexual function concerns most influential. Impact on work and recreation activities also influential. Majority (70%) reported a specific influence of age on treatment outcomes.
Bosco et al4 When side effects influenced treatment decisions, most commonly combination of all three (bowel, bladder, and sexual) rather than one or two. Less than half of patients chose treatment option concordant with stated concerns.
Chapple et al5 This qualitative study found that men who choose AS face pressure from family members to pursue active treatment.
Davison et al6 Four main factors influenced management decisions: urologist’s recommendation, impact of treatment on urinary function, age at time of diagnosis, and impact of treatment on sexual function.
de Bekker-Grob et al7 Patients with anxious/depressed feeling were more likely to choose EBRT or RP than AS. Management choices were influenced by treatment modality and risk of urinary incontinence.
Gwede et al8 Patients who chose surgery stated a desire for best chance for cure. Patients who chose BT did so because it was the least painful, least invasive, promised to have the fewest side effects, was convenient, and avoided surgery.
Hall et al9 Patients who choose prostatectomy are more likely to state that the reason is evidence that it is the best procedure to cure their cancer. Patients who choose prostate BT are more likely to state that they did so because of side-effect profile.
BT patients were more likely to report their decision was influenced by a physician’s preference than were RP patients.
Holmboe et al10 The most common dislikes for RP were incontinence and impotence, and the most common like was tumor removal.
The most common dislikes of EBRT were long duration of treatment and diffuse targeting. The most common likes for BT were short duration of treatment, noninvasive, and focused targeting, while weak evidence was cited as a dislike. Intrinsic characteristics of treatment were cited more commonly than likelihood of side effects as a reason for choosing treatment.
Ihrig et al11 Concerns for possible treatment side effects were cited as a reason for choosing EBRT. Patients who chose RP were more likely to cite personal beliefs regarding surgery as a reason.
Mazur et al12 Most patients who preferred RP reported that their choice was most influenced by desire for complete cancer removal. Most patients who chose AS reported that avoiding surgical complications was their top priority.
Mazur et al13 One quarter of men in this study preferred AS even when RP was assumed to have a 10-year survival benefit.
Older patients were also more likely to prefer AS.
Ramsey et al14 Men who choose RP are less likely to rank chances of problems with sexual function as very important. Men who rank convenience as a priority are more likely to choose BT.
Sidana et al15 Doctor’s recommendation was the most commonly cited reason for choosing a treatment. Among those who chose RP over RT, the most common reasons were best chance of cure, doctor recommended, and young age. Among those who chose RT over RP, the most common reasons were less invasive and fewer side effects.
Sommers et al16 The strongest predictor of management choice was type of physician seen when the survey was administered.
QALYs for health states did not predict treatment choice.
Steginga et al17 Open-ended questions revealed that the most concerning side effects for RP are incontinence and impotence.
The most concerning side effects for EBRT are bowel problems and skin burns.
van Tol-Geerdink et al18 Patients preferring BT valued sexual problems and convenience of the treatment more than patients choosing RP or EBRT.
Xu et al19 Perceptions of treatment efficacy and risks of side effects were the most influential contributors to patient preferences.
Xu et al20 Knowledge of AS is limited, and some men yield to pressure from family members and physicians to choose active treatment over AS.
Zeliadt et al21 Men who were concerned about the burden of treatment were more likely to prefer options other than RP. Men who prioritized treatment efficacy were more likely to consider only RP.
Zeliadt et al22 Men who prioritized risk of adverse effects were more likely to prefer nonsurgical options.

Abbreviations: AS, active surveillance; BT, brachytherapy; EBRT, external beam radiation therapy; QALYs, quality-adjusted life years; RP, radical prostatectomy.