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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Virology. 2015 Jan 9;476:334–340. doi: 10.1016/j.virol.2014.12.020

Fig. 1.

Fig. 1

IFNL4 is anti-viral against infectious Flaviviridae. (A) Relative positions of IFNL3 and IFNL4 mRNAs are indicated along with locations of genetic variants relevant to this study. Proteins produced by IFNL4 transcripts are indicated for the rs368234815 ΔG genotype. (B) Huh7.5 cells transiently transfected with the indicated expression plasmids were infected with HCV, DENV2, or YFV-17D and rates of infection were measured by quantitative immunofluorescence using antibodies against viral antigens. All data are shown as mean±S.D. (C) Representative immunofluorescence images that illustrate levels of virus infection after transfection with the indicated plasmids are shown.