Table 3.
Association of each atherosclerotic risk factor and adjusted mortality in patients with and without cardiovascular risk factors and first myocardial infarction: National Registry of Myocardial Infarction, 1994 to 2006
| Risk Factor | Odds Ratio (95% Confidence Interval) |
Wald Chi- Square |
|---|---|---|
| Model 1: age by 10-year intervals |
1.77 (1.75–1.78) | 21,027 |
| Model 2: age, atherosclerotic risk factors (n = 5) |
||
| Diabetes mellitus | 1.35 (1.32–1.38) | 727 |
| Hypertension | 0.89 (0.88–0.91) | 127 |
| Smoking | 0.93 (0.90–0.95) | 31 |
| Family history of CHD | 0.62 (0.60–0.64) | 1,231 |
| Dyslipidemia | 0.49 (0.48–0.51) | 2,684 |
| Model 3: age, atherosclerotic risk factors, weight |
||
| Diabetes mellitus | 1.41 (1.38–1.44) | 947 |
| Hypertension | 0.91 (0.89–0.92) | 98 |
| Smoking | 0.89 (0.87–0.92) | 72 |
| Family history of CHD | 0.63 (0.61–0.64) | 1,152 |
| Dyslipidemia | 0.51 (0.49–0.52) | 2,484 |
| Model 4: full model | ||
| Diabetes mellitus | 1.23 (1.20–1.26) | 299 |
| Hypertension | 1.08 (1.06–1.11) | 56 |
| Smoking | 0.85 (0.83–0.88) | 122 |
| Family history of CHD | 0.71 (0.69–0.73) | 545 |
| Dyslipidemia | 0.62 (0.60–0.64) | 1,071 |
| Age by 10-year intervals | 1.43 (1.41–1.44) | 3,397 |
| Weight (kg) | ||
| <50 | 1.16 (1.11–1.21) | 50 |
| 50–<60 | 1.00 (referent) | |
| 60–<70 | 0.93 (0.90–0.96) | 18 |
| 70–<80 | 0.87 (0.84–0.90) | 57 |
| 80–<90 | 0.79 (0.76–0.83) | 133 |
| 90–<100 | 0.76 (0.73–0.80) | 132 |
| 100–<110 | 0.76 (0.71–0.80) | 87 |
| 110–<120 | 0.85 (0.79–0.92) | 17 |
| ≥120 | 0.93 (0.87–0.99) | 5 |
| Female gender | 0.99 (0.96–1.01) | 2 |
| Race/ethnicity | ||
| White | 1.00 (referent) | |
| African American/black | 1.05 (1.00–1.09) | 5 |
| Asian/Pacific-Islander | 1.06 (0.99–1.14) | 3 |
| Hispanic | 1.00 (0.95–1.06) | 0 |
| Insurance | ||
| Medicare | 1.36 (1.32–1.41) | 351 |
| Medicaid and/or uninsured | 1.36 (1.30–1.43) | 183 |
| Systolic blood pressure | 0.98 (0.98–0.98) | 10,002 |
| Pulse | 1.01 (1.01–1.01) | 2,178 |
| Prehospital delay (hours) | ||
| 0–2 | 1.00 (referent) | |
| 2–<4 | 0.80 (0.76–0.83) | 129 |
| ≥4 | 0.97 (0.94–1.00) | 4 |
| Killip class | ||
| I | 1.00 (referent) | |
| II | 1.52 (1.48–1.56) | 949 |
| III | 1.91 (1.85–1.98) | 1,250 |
| IV | 8.30 (7.84–8.78) | 5,352 |
| Calendar year | 0.97 (0.96–0.97) | 317 |
| ST-segment or left bundle branch block |
1.74 (1.70–1.78) | 2,000 |
| MI location (anterior) | 1.27 (1.24–1.30) | 417 |
| Admission diagnosis | ||
| Unstable angina/other | 1.00 (referent) | |
| MI | 0.76 (0.75–0.78) | 428 |
| Rule out MI | 0.51 (0.49–0.53) | 1,647 |
| MI volume quartile | ||
| 1 | 1.00 (referent) | |
| 2 | 1.02 (0.97–1.07) | 0 |
| 3 | 1.01 (0.96–1.06) | 0 |
| 4 | 0.99 (0.94–1.04) | 0 |
| Percutaneous coronary intervention noncapable |
1.00 (referent) | |
| Interventional | 0.65 (0.63–0.67) | 882 |
| Interventional without open-heart surgery |
0.79 (0.76–0.83) | 103 |
| Census region | ||
| East | 1.00 (referent) | |
| West | 1.15 (1.11–1.19) | 62 |
| South | 1.24 (1.19–1.28) | 152 |
| Midwest | 1.14 (1.10–1.17) | 54 |
| Hospital type | ||
| Nonurban | 1.00 (referent) | |
| Urban teaching | 0.99 (0.94–1.04) | 0 |
| Urban nonteaching | 0.99 (0.96–1.03) | 0 |