Ferraz 1991.
Methods | Randomised, double‐blind, placebo control, 2 group crossover. Duration 3 weeks (2 x 1 week crossover, 1 week washout) | |
Participants | Randomised n=22, Completed n=20. Mean age 62 yrs, range 47‐78 yrs. Inclusion: OA hip or knee, clinical and radiographic verification (criteria not specified) | |
Interventions | Tipi tea: Petiveria alliacea, aqueous extract, 3 x 200ml tea (equivalent to 9gm tipi) Placebo control: Sape, Imperata exaltata (dose not specified) |
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Outcomes | Pain (scale not reported) at rest, pain with mvt, pain at night, 15 metre walking time, MACTAR patient preference questionnaire | |
Notes | Exploratory study design; power, effect, and sample size not determined a priori. Did not report ethical oversight or compliance with guidelines. Results equivocal. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Described as randomised, method not reported |
Allocation concealment (selection bias) | Unclear risk | Allocation concealment not reported |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Described as double‐blind, method not reported |
Incomplete outcome data (attrition bias) All outcomes | High risk | Brief report. Full report not available (high risk) Reported withdrawals (low risk) |
Selective reporting (reporting bias) | Low risk | Reported adverse events (low risk) |
Other bias | High risk | Criteria for diagnosis of OA not specified (high risk) Financial and in kind support not reported |