Table 1.

Grade independent basal phenotype miRNA signature in common with other studies [12, 13, 49, 50]

	miRNA in common with other studies	Unadjusted p value	Adjusted p value	Fold change	Expression in basal vs. luminal
hsa-miR-149	[14, 16]	0.0246	0.2556	−2.21	Down
hsa-miR-29c	[14–16, 50, 51]	0.0315	0.2838	−1.22	Down
hsa-miR-29c*	[15, 16, 50]	0.0278	0.2679	−1.61	Down
hsa-miR-109b	[14, 50]	<0.0001	<0.0001*	−11.77	Down
hsa-miR-125a-5p	[14]	0.0203	0.2292	−1.13	Down
hsa-miR-136	[12]	0.0247	0.1120	−1.78	Down
hsa-miR-199a*:9.1	[12]	0.0138	0.0777	−1.47	Down
hsa-miR-342-3p	[14–16]	0 < 0.0001	0.0024*	−1.58	Down
hsa-miR-342-5p	[12–16, 49]	<0.0001	0.0001*	−1.97	Down
hsa-miR-375	[15, 16, 50]	0.0005	0.0177	−3.56	Down
hsa-let-7c	[12, 15]	0.0020	0.0232*	−1.26	Down
hsa-let-7f	[12]	0.0300	0.1284	−1.11	Down
hsa-let-7a	[12]	0.0467	0.1669	−1.05	Down
hsa-miR-17	[15, 16, 50]	<0.0001	0.0002*	1.74	Up
hsa-miR-17*	[14–16, 50]	0.0004	0.0162*	1.30	Up
hsa-miR-18a	[12–16, 32, 50, 52]	<0.0001	<0.0001*	5.22	Up
hsa-miR-18b	[14–16, 50]	0.0269	0.2676	1.89	Up
hsa-miR-19a	[14–16, 50]	0.0006	0.0191*	3.37	Up
hsa-miR-19b	[15, 16]	0.0005	0.0171*	1.90	Up
hsa-miR-93	[12, 13, 16]	0.0001	0.0032*	1.30	Up
hsa-miR-106a	[12, 13, 50]	<0.0001	0.0011*	1.87	Up
hsa-miR-106b	[12, 13, 15, 50]	0.0151	0.0814	1.59	Up
hsa-miR-135b	[12–16, 50]	<0.0001	0.0017*	4.44	Up
hsa-miR-142-5p	[12, 13]	0.0019	0.0229*	2.07	Up
hsa-miR-20a	[15, 16]	<0.0001	0.0001*	1.51	Up
hsa-miR-224	[14, 16]	0.0004	0.0162	4.75	Up
hsa-miR-455-5p	[14]	0.0159	0.1986	2.08	Up
hsa-miR-505	[50]	0.0030	0.0741	2.83	Up
hsa-miR-519a	[14]	<0.0001	0.0007*	9.05	Up
hsa-miR-521	[14]	<0.0001	<0.0001*	8.97	Up
hsa-miR-522	[14]	<0.0001	0.0004*	10.79	Up
hsa-miR-9	[14]	0.0069	0.1260	4.60	Up
hsa-miR-9*	[14, 16]	0.0322	0.2838	2.50	Up
hsa-miR-93	[15, 16]	0.0003	0.0142	1.32	Up

*significant p < 0.05 after adjustment for multiple tests