Fig. 9.
Gene expression of hMSCs cultured on silk scaffolds, SHG ceramic scaffolds, SHG-silk scaffolds and biphasic scaffolds in osteogenic medium over 21 days, expressed as fold increase from undifferentiated cells at day 0. (A, B) Runx2, (C, D) collagen type I, (E, F) alkaline phosphatase, and (G, H) bone sialoprotein. (A, C, E, G) show differences in expression levels between groups (*p < 0.05 between groups) while (B, D, F, H) show changes in expression levels within each group over the culture period (#p < 0.05 within the same group compared to previous time point).