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Number of interacting partners found in both replicated experiments of MCC-AP-MS/MS (FDR < 10%) and AP-MS/MS (FDR < 20%) for each bait (POLR2A, CDK9 and RPAP4). We allowed a higher FDR threshold for AP-MS/MS derived interactions to match previous studies.17 This only advantages AP-MS/MS over MCC-AP-MS/MS in this comparison.
