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. 2015 May 18;6(14):11979–11993. doi: 10.18632/oncotarget.3979

Figure 5. Effects of losartan treatment on downstream effectors of AT1R and antioxidants.

Figure 5

Western blot analyses of cardiac protein extracts from aged WT (aWT) A., young IL-10−/− (yKO) E., and aged IL-10−/− (aKO) I. mice with (+L) or without losartan treatment using antibodies against NADPH oxidases (Nox) 2 and 4 and Catalase (Cat). Actin was used as a loading control. Relative expression was calculated for the Western blots displayed in arbitrary units (AU) for aWT B–D., yKO F–H. and aKO J–L. Data are means ± SEM. *p < 0.05, **p < 0.01.