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A. Cardiac hypertrophy measured as a ratio of heart weight to tibia length of aged WT (aWT) mice, aWT with (+L) losartan treatment, aged IL-10−/− (aKO) and aKO+L B. Quantification of fibrosis evident in Masson Trichrome stain C. Scale bar: 100 μm. D. Fractional shortening and E. isovolumetric relaxation time (IVRT) of aged WT and aged IL-10−/− with (+L) and without losartan treatment. Data are means ± SEM *p < 0.05.
