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. 2015 Mar 26;6(14):12174–12187. doi: 10.18632/oncotarget.3650

Figure 6. MARCH7 regulated tumorigenesis in nude mice model.

Figure 6

(A, B) Mean tumor volume and weight on day 21 after tumor cell injection. LV3-shMARCH7-1 or LV3-NC infected SKOV3 cells were implanted s.c. into the left armpit. (C). Immunohistochemical analysis of MARCH7, NFkB P65, NFkB P50, and β-catenin expression were performed on tumor xenografts. Representative images are shown (original magnification ×200). (D, E) Mean tumor volume and weight on day 21 after tumor cell injection. LV5-GFP or LV5-MARCH7 infected A2780 cells were implanted s.c. into the left armpit. (F) Immunohistochemical analysis of MARCH7, NFkB P65, NFkB P50, and β-catenin expression were performed on tumor xenografts. Representative images are shown (original magnification ×200). * p < 0.05, and **p < 0.001.