Table 1. Correlation between relative PAQR3 expression level and clinicopathologic parameters of the patients.
| Variables | n | PAQR3 mRNA level | χ2 | ||
|---|---|---|---|---|---|
| Low | Normal/High | (P-value) | |||
| Age (years) | |||||
| <50 | 50 | 39 | 11 | 3.270 | |
| ≥50 | 32 | 19 | 13 | (0.071) | |
| Tumor location | |||||
| Left | 44 | 31 | 13 | 0.004 | |
| Right | 38 | 27 | 11 | (0.953) | |
| Tumor size | |||||
| ≤2 cm | 39 | 27 | 12 | 0.081 | |
| >2 cm | 43 | 31 | 12 | (0.776) | |
| Differentiation | |||||
| Moderate/high | 34 | 11 | 23 | 41.326 | |
| Poor | 48 | 47 | 1 | (1.289E-10) | |
| T stage | |||||
| I/II | 67 | 47 | 20 | 0.060 | |
| III/IV | 15 | 11 | 4 | (0.806) | |
| Lymph node metastasis | |||||
| Negative | 38 | 24 | 14 | 1.962 | |
| Positive | 44 | 34 | 10 | (0.161) | |
| TNM stage | |||||
| I/II | 55 | 35 | 20 | 4.062 | |
| III/IV | 27 | 23 | 4 | (0.044) | |
| ER status | |||||
| Negative | 44 | 30 | 14 | 0.298 | |
| Positive | 38 | 28 | 10 | (0.585) | |
| Her2 status | |||||
| Negative | 29 | 6 | 23 | 54.274 | |
| Positive | 53 | 52 | 1 | (1.744E-13) | |
| PR status | |||||
| Negative | 42 | 35 | 14 | 0.029 | |
| Positive | 39 | 23 | 10 | (0.866) | |
Note: n, number of patients; ER, estrogen receptor; PR, progesterone receptor; Her2, human epidermal growth factor receptor 2; TNM, tumor, node, metastasis. Fisher's exact test was used for statistical analyses. PAQR3 mRNA low expression is defined as tumor/PCHNT < 0.5 and normal/high expression as tumor/PCHNT >= 0.5.