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. 2015 Feb 3;6(14):12421–12435. doi: 10.18632/oncotarget.3043

Figure 7. SI221 reduces RMS cell growth in xenotrasplanted mice.

Figure 7

(A) Growth curves of RD xenografts in 2 groups of nude mice treated with vehicle alone (control) or SI221, respectively. The reported values represent the means and standard errors of the tumor volumes at each measurement. Statistically significant differences between the mean tumor volumes of control mice and SI221-treated mice were evaluated by Student t test at each evaluation time and indicated with *: significant (P < 0.05) and **: very significant (P < 0.01). (B) Dot plots showing the means and standard deviations of the weights of tumors excised from control mice and SI221-treated mice at the end of treatment. Statistical significance was evaluated through Student t test and indicated with**: very significant (P < 0.01).