Table 1. Differentially expressed genes after 10 passages in cell lines with and without inhibition of mutant IDH1 using AGI-5198 (FDR<0.05).
The expression levels are shown in Reads per Kilobase per Million (RPKM)
Chr | GeneID | HT1080 p10 AGI-5198 (RKPM) | HT1080 p10 control (RKPM) | JJ012 p10 AGI-5198 (RKPM) | JJ012 p10 control (RKPM) | L835 p10 AGI-5198 (RKPM) | L835 p10 control (RKPM) |
---|---|---|---|---|---|---|---|
Chr7 | CHRM2 | 0 | 0 | 0 | 0 | 2.391 | 0.011 |
Chr6 | SIM1 | 0 | 0 | 0.024 | 0 | 0.848 | 0.063 |