Table 1. Association of USP22 expression with patient's characteristics in hepatocellular carcinoma.
| Variable | All cases | Training set (n = 45) | Testing set (n = 59) | ||||
|---|---|---|---|---|---|---|---|
| High expression | Low expression | pa | High expression | Low expression | pa | ||
| Age (years) | 0.259 | 0.6481 | |||||
| ≥50.00 b | 57 | 12(26.7%) | 14(31.1%) | 17(28.8%) | 14(23.7%) | ||
| <50.00 | 47 | 12(26.7%) | 7(15.5%) | 17(28.8%) | 11(18.6%) | ||
| Gender | 1 | 0.061 | |||||
| Male | 94 | 23(51.1%) | 20(44.4%) | 32(54.2%) | 19(32.2%) | ||
| Female | 10 | 1(0.2%) | 1(0.2%) | 2(3.4%) | 6(10.2%) | ||
| Clinical stage | 0.002 | 0.026 | |||||
| I+II | 30 | 4(8.9%) | 13(28.9%) | 4(6.8%) | 9(15.3%) | ||
| III+IV | 74 | 20(44.4%) | 8(17.8%) | 30(50.8%) | 16(27.1%) | ||
| Tumor size (cm) | 0.003 | 0.829 | |||||
| ≤5 | 48 | 9(20.0%) | 17(37.8%) | 9(15.3%) | 6(10.2%) | ||
| >5 | 56 | 15(33.3%) | 4(8.9%) | 25(42.3%) | 19(32.2%) | ||
| AFP (ng/mL) | 0.202 | 0.113 | |||||
| <200 | 57 | 19(42.2%) | 13(28.9%) | 29(49.2%) | 17(28.8%) | ||
| ≥200 | 47 | 5(11.1%) | 8(17.8%) | 5(8.5%) | 8(13.5%) | ||
| Edmonson grade | 0.004 | 0.001 | |||||
| 1-2 | 80 | 16(35.5%) | 21(46.7%) | 19(32.2%) | 24(40.7%) | ||
| 3-4 | 24 | 8(17.8%) | 0(0%) | 15(25.4%) | 1(1.7%) | ||
| Tumor number | 0.259 | 0.589 | |||||
| solitary | 59 | 12(26.7%) | 14(31.1%) | 18(30.5%) | 15(25.4%) | ||
| mutiple | 45 | 12(26.7%) | 7(15.5%) | 16(27.2%) | 10(16.9%) | ||
a
x2 test.
b
median age