Table 1.

Clinical Characteristics of Study Cohorts at Enrollment

	Cohort 1 (n=17)	Cohort 2 (n=35)
Females	7 (41%)	15 (43%)
Age (Years – Median, Range)	13 (8 to 20)	12 (6 to 15)
CF Genotype
ΔF508 homozygous	7 (44%)	14 (40%)
ΔF508 heterozygous	6 (38%)	15 (43%)
Other/Other	3 (19%)	6 (17%)
FEV1, % predicted (mean +/− SD)	99.3 ± 19.1	95.3 ± 15.0
Total number of study visits	48	134
Number of IS samples collected	48 (100%)	101 (93%)
Number of ES samples collected	38 (79%)	58 (57%)
Number of OP samples collected	47 (98%)	43 (43%)