TABLE II.

Germline Mutations Predicting p.Gly12Val in Patients With Severe Costello Syndrome

Patient	Nucleotide substitution
1	c.35_36delinsTA
2	c.35_36delinsTT
3	c.35_36delinsTT
4	c.35G > T
Aoki et al. [2005] (Patient COS37)	c.35_36delinsTT
van der Burgt et al. [2007] (Patient 1)	c.35_36delinsTT