Table 3. Antioxidant activities in serotonin deficient mice.

Oxidants	pCPA-treated mice		Tph2-/- mice
	Control group (n = 20)	pCPA-treated group (n = 20)	Control group (n = 20)	Tph2-/- group (n = 20)
ROS (1/mgpr)	17.61 ± 1.99	29.84 ± 3.21*	20.46 ± 2.21	34.62 ± 2.11*
MDA (μmol/L)	2.24 ± 0.44	3.16 ± 0.88*	2.03 ± 0.36	3.38 ± 1.12*
T-AOC (mmol/L FeSO4)	1.32 ± 0.14	0.94 ± 0.07*	1.62 ± 0.21	0.72 ± 0.11*
SOD (U/mL)	1.14 ± 0.10	0.72 ± 0.04*	1.44 ± 0.11	0.62 ± 0.07*
CAT (U/mL)	0.16 ± 0.024	0.13 ± 0.0088*	0.14 ± 0.011	0.079 ± 0.0084*
GPx (U/mL)	2.72 ± 0.33	1.82 ± 0.094*	2.46 ± 0.19	1.64 ± 0.19*

ROS, reactive oxygen species; MDA, malondialdehyde; T-AOC, total antioxidant capacity; SOD, superoxide dismutase; CAT, catalase; GPx, glutathione peroxidase.

Data are expressed as mean values ± standard deviation.

^*p-value < 0.05 compared with control group. P-values were determined by the Mann-Whitney U test.