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. 2015 Jun 11;11(8):948–960. doi: 10.7150/ijbs.12468

Fig 3.

Fig 3

Overexpression of FGF9 in prostatic epithelial cells promotes PCa progression in mice. A. In situ hybridization showing expression of Fgf9 mRNA in mouse prostates. B. Real-time RT-PCR analyses of Fgf9 expression in TRAMP and F9TRAMP prostates at 4 months. C. Statistical analysis of prostate/body weight ratio of TRAMP and F9TRAMP prostates at the ages of 4, 5, and 6 months. D. H&E staining of TRAMP and F9TRAMP prostates at the ages of 3, 4, and 6 months. E. Quantitative analyses of prostate lesions of TRAMP and F9TRAMP mice at the age of 3 or 6 months. N=5 per group. F. Immunostaining comparing AR, P63, and Ki67 expression in TRAMP and F9TRAMP prostates. Panel g, statistical analyses of proliferating cells in TRAMP and F9TRAMP prostates at the indicated ages. Scale bars, 50 µm